CBD for Seizures in Dogs: Adjunct Therapy for Epilepsy

CBD for Seizures in Dogs: Adjunct Therapy for Epilepsy

Many owners explore CBD for dog seizures when conventional antiepileptics fail to fully control epilepsy.

  • Colorado State (2019): Dogs receiving 2.5 mg/kg CBD twice daily had 33% fewer seizures on average.

  • Not all dogs respond—highlighting variability in seizure threshold and drug metabolism.

Mechanism: CBD modulates GABA and glutamate signaling and may act on GPR55 receptors to reduce excitability.

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Important to know for pet owners

  • CBD may reduce seizure frequency, but it is not a cure.

  • Always continue prescribed anticonvulsants unless a veterinarian directs otherwise.

  • Consistency in dosing and product quality is critical.

Important to know for veterinarians

  • CBD shows promise as an adjunctive therapy, not a replacement for phenobarbital or potassium bromide.

  • Monitor seizure logs closely with owners to evaluate response.

  • Bloodwork (CBC, chem panel, liver enzymes) is advisable during treatment.

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